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Adrenal Glands: Functions, Health Importance, and Signs of Dysfunction

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(Audio) Adrenal Glands

The adrenal glands, small but mighty, play a crucial role in maintaining balance in the body. Sitting atop each kidney, these triangular-shaped glands are part of the endocrine system and produce essential hormones that influence metabolism, immune response, blood pressure, stress response, and more. Supporting adrenal health is vital for energy, resilience, and overall well-being.


What Do the Adrenal Glands Do?

The adrenal glands are divided into two main regions: the cortex and the medulla. Each part releases different hormones:

  • Adrenal Cortex: Produces corticosteroids such as cortisol, which helps control metabolism, inflammation, energy, and the stress response; weak androgens such as DHEA & DHEA-S that will be converted to testosterone and estrogen; as well as aldosterone, which helps regulate blood pressure and electrolyte balance.

  • Adrenal Medulla: Produces adrenaline (epinephrine) and noradrenaline (norepinephrine), hormones involved in the body’s "fight or flight" response.

These hormones work in harmony to keep your body functioning optimally, especially under stress.

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Why Is Adrenal Health Important?

When the adrenal glands function properly, they help the body respond to physical and emotional stress, maintain stable energy levels, and support immune and cardiovascular health. However, modern lifestyles filled with chronic stress, poor sleep, processed foods, and environmental toxins can overburden the adrenals, leading to dysfunction.


Signs and Symptoms of Adrenal Dysfunction

Adrenal dysfunction can present in many ways, depending on whether the glands are under- or over-producing hormones. Some common signs include:

  • Fatigue, especially upon waking

  • Difficulty coping with stress

  • Brain fog or trouble concentrating

  • Salt and sugar cravings

  • Low blood pressure or dizziness when standing

  • Mood swings or irritability

  • Poor sleep or insomnia

  • Unexplained weight loss or gain

These symptoms are often non-specific, making adrenal issues easy to overlook or misdiagnose.


Lifestyle Choices Supporting Adrenal Health

To protect and support your adrenal glands:

  • Get 7–9 hours of quality sleep each night

  • Maintain a consistent sleep and eating schedule

  • Manage stress with mindfulness, meditation, therapy, or other calming activities

  • Eat balanced, whole-food meals rich in protein, healthy fats, and complex carbs

  • Ensure proper and adequate nutrient intake

  • Avoid excess caffeine, sugar, and alcohol

  • Exercise regularly but avoid overtraining

  • Avoid smoking and smokeless nicotine


When to See a Doctor

If you’re experiencing persistent fatigue, unexplained weight changes, or other symptoms of adrenal dysfunction, it’s essential to consult a healthcare provider. Blood, urine, and saliva tests can help assess hormone levels and adrenal function.


Conclusion

Your adrenal glands are vital for energy, resilience, and overall vitality. Supporting their health through lifestyle choices and early recognition of symptoms can prevent more serious hormonal imbalances. While adrenal fatigue remains a debated diagnosis, the impacts of stress and hormone disruption on adrenal function are very real and deserve attention.


Disclaimer: The information provided in this article is for informational and educational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before making changes to your diet, lifestyle, or health care regimen.


References

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  2. Tsigos C, Chrousos GP. Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress. J Psychosom Res. 2002;53(4):865-871. doi:10.1016/S0022-3999(02)00429-4

  3. Herman JP, McKlveen JM, Solomon MB, Carvalho-Netto E, Myers B. Neural regulation of the stress response: glucocorticoid feedback mechanisms. Braz J Med Biol Res. 2012;45(4):292-298. doi:10.1590/S0100-879X2012007500041

  4. Chrousos GP. Stress and disorders of the stress system. Nat Rev Endocrinol. 2009;5(7):374-381. doi:10.1038/nrendo.2009.106

  5. McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med. 1998;338(3):171-179. doi:10.1056/NEJM199801153380307

  6. Juster RP, McEwen BS, Lupien SJ. Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev. 2010;35(1):2-16. doi:10.1016/j.neubiorev.2009.10.002

  7. Antoniou-Tsigkos A, Zapanti E, Ghizzoni L, et al. Adrenal androgens. In: Feingold KR, Ahmed SF, Anawalt B, et al., eds. Endotext [Internet]. South Dartmouth, MA: MDText.com, Inc.; 2000–. Updated January 5, 2019. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278929/

  8. Papadopoulou-Marketou N, Kassi E, Chrousos GP. Adrenal androgens and aging. In: Feingold KR, Ahmed SF, Anawalt B, et al., eds. Endotext [Internet]. South Dartmouth, MA: MDText.com, Inc.; 2000–. Updated January 18, 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279006/



©2025 by Nazanin Safaei, ND, MS

©2023 by Vivid Health Naturopathic.

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